NFL Week 5 Odds: Bills Laying Huge Number, Ravens Host Rival Bengals

by -

The 2022 NFL season continues to roll on, and Week 5 brings us our second London game, one of the largest spreads we’ve had this season, and two high-powered primetime divisional matchups.

Let’s look at Week 5 NFL odds across the top online sportsbooks. If any of these Week 5 spreads, moneylines, or totals stand out to you, there are thousands of dollars in sportsbook promos available to get some skin in the game.

Claim a $1,000 Risk-Free Bet with BetMGM Bonus Code ROCKYBET

NFL Week 5 Odds

Here are the odds for every NFL Week 5 game from BetMGM Sportsbook as of Monday afternoon, Oct. 3.

DATE/TIMEMATCHUPPOINT SPREADMONEYLINETOTAL
Thursday, Oct. 6, 7:15 p.m. CTIndianapolis Colts at Denver BroncosIndianapolis +3.5 (-110)
Denver -3.5 (-110)
Indianapolis +150
Denver -185
Over 43.5 (-110)
Under 43.5 (-110)
Sunday, Oct. 9, 8:30 a.m. CTNY Giants vs. Green Bay PackersNY Giants +8 (-110)
Green Bay -8 (-110)
NY Giants +275
Green Bay -350
Over 41.5 (-110)
Under 41.5 (-110)
Sunday, Oct. 9, Noon CTPittsburgh Steelers at Buffalo BillsPittsburgh +14 (-110)
Buffalo -14 (-110)
Pittsburgh +600
Buffalo -900
Over 47.5 (-110)
Under 47.5 (-110)
Sunday, Oct. 9, Noon CTLA Chargers at Cleveland BrownsLA Chargers -3 (-105)
Cleveland +3 (-115)
LA Chargers -160
Cleveland +135
Over 48 (-110)
Under 48 (-110)
Sunday, Oct. 9, Noon CTChicago Bears at Minnesota VikingsChicago +7 (-115)
Minnesota -7 (-105)
Chicago +240
Minnesota -300
Over 44 (-110)
Under 44 (-110)
Sunday, Oct. 9, Noon CTDetroit Lions at New England PatriotsDetroit +3 (-115)
New England -3 (-105)
Detroit +120
New England -145
Over 46.5 (-110)
Under 46.5 (-110)
Sunday, Oct. 9, Noon CTSeattle Seahawks at New Orleans SaintsSeattle +5.5 (-110)
New Orleans (-110)
Seattle +180
New Orleans -225
Over 45.5 (-110)
Under 45.5 (-110)
Sunday, Oct. 9, Noon CTMiami Dolphins at NY JetsMiami -3 (-115)
NY Jets +3 (-105)
Miami -165
NY Jets +140
Over 43.5 (-110)
Under 43.5 (-110)
Sunday, Oct. 9, Noon CTAtlanta Falcons at Tampa Bay BuccaneersAtlanta +8.5 (-110)
Tampa Bay -8.5 (-110)
Atlanta +300
Tampa Bay -375
Over 48.5 (-110)
Under 48.5 (-110)
Sunday, Oct. 9, Noon CTTennessee Titans at Washington CommandersTennessee -2.5 (-115)
Washington +2.5 (-105)
Tennessee -150
Washington +125
Over 42.5 (-110)
Under 42.5 (-110)
Sunday, Oct. 9, Noon CTHouston Texans at Jacksonville JaguarsHouston +7 (-105)
Jacksonville -7 (-115)
Houston +260
Jacksonville -350
Over 44.5 (-110)
Under 44.5 (-110)
Sunday, Oct. 9, 3:05 p.m. CTSan Francisco 49ers at Carolina PanthersSan Francisco -5 (-110)
Carolina +5 (-110)
San Francisco -225
Carolina +185
Over 39.5 (-110)
Under 39.5 (-110)
Sunday, Oct. 9, 3:25 p.m. CTDallas Cowboys at LA RamsDallas +4.5 (-110)
LA Rams -4.5 (-110)
Dallas +200
LA Rams -250
Over 45.5 (-110)
Under 45.5 (-110)
Sunday, Oct. 9, 3:25 p.m. CTPhiladelphia Eagles at Arizona CardinalsPhiladelphia -5.5 (-115)
Arizona +5.5 (-110)
Philadelphia -225
Arizona +185
Over 49.5 (-110)
Under 49.5 (-110)
Sunday, Oct. 9, 7:20 p.m. CTCincinnati Bengals at Baltimore RavensCincinnati +3 (-105)
Baltimore -3 (-115)
Cincinnati +155
Baltimore -185
Over 48.5 (-105)
Under 48.5 (-115)
Monday, Oct. 10, 7:15 p.m. CTLas Vegas Raiders at Kansas City ChiefsLas Vegas +7 (-105)
Kansas City -7 (-115)
Las Vegas +260
Kansas City -350
Over 51 (-110)
Under 51 (-110)

Week 5 NFL Games to Watch

Indianapolis Colts at Denver Broncos (-3.5, 43.5)

Week 5 kicks off with a matchup between two teams who have yet to live up to their offseason expectations in the Colts and Broncos. Both teams are 1-3 against the spread while Denver is the only team of the two to have had a game hit the over so far this season. The Colts and Broncos are a combined 7-1 in favor of the under through four weeks. Both teams could be without their top running back as Javonte Williams suffered a major knee injury on Sunday, and Jonathan Taylor is dealing with an ankle injury.

Score $1,250 in sports betting bonuses with DraftKings Promo Code

Pittsburgh Steelers at Buffalo Bills (-14, 47.5)

In the largest spread of Week 5 and one of the highest this season, the Steelers head to New York to take on the Bills. Will we see Steelers’ rookie Kenny Pickett get his first start in Week 5 after replacing Mitchell Trubisky this past week?

Historically, the Bills are 8-7-3 against the spread (ATS) in games they are favored by 14 or more points. Since 2019 with Josh Allen under center, Buffalo is 3-2-2 in such games. As double-digit dogs, the Steelers are 7-5 all-time ATS and 1-2 ATS under head coach Mike Tomlin.

Dallas Cowboys at Los Angeles Rams (-4.5, 45.5)

The spread on this game has dropped 1.5 points between Sunday night and Monday morning. Going back to last week’s lookahead line, it has dropped even further as the Rams were 7-point favorites on Sept. 30. Could this signal the return of Dak Prescott for the Cowboys?

Cincinnati Bengals at Baltimore Ravens (-3, 48.5)

We get a fantastic matchup for Week 5 Sunday Night Football between two AFC North rivals. With the Bengals, Ravens, and Browns all currently sitting at 2-2, this is a pivotal matchup for the divisional race. Cincy will look to win its third straight game as Baltimore tries to bounce back after blowing a 20-3 lead versus Buffalo.

Las Vegas Raiders at Kansas City Chiefs (-7, 51)

Week 5 wraps up with another divisional primetime game between the Raiders and the Chiefs. This is by far the highest total on the week as no other game is above 50. On the season, Kansas City is 2-2 ATS while Las Vegas is 1-3. The two teams are a combined 4-3-1 in favor of the over. In their last 10 matchups, Kansas City is 6-4 against the spread and the over has hit in 60% of those games.